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文章摘要
MU Shousun.Cost-effectiveness Analysis of Pantoprazole Versus Omeprazole in the Treatment of Gastric Ulcer[J].中国药物评价,2019,36(3):236-240
泮托拉唑对比奥美拉唑治疗胃溃疡的成本效果分析
Cost-effectiveness Analysis of Pantoprazole Versus Omeprazole in the Treatment of Gastric Ulcer
投稿时间:2019-05-21  修订日期:2019-05-21
DOI:
中文关键词: 泮托拉唑  奥美拉唑  胃溃疡  决策树模型  成本效果分析
英文关键词: Pantoprazole  Omeprazole  Gastric ulcer  Decision tree model  Cost-effectiveness analysis
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作者单位E-mail
穆守荪 中国药科大学国际医药商学院 mushousun9431@163.com 
刘永军 中国药科大学国际医药商学院 yongjunliu@163.com 
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中文摘要:
      目的:运用药物经济学方法研究和评价泮托拉唑对比奥美拉唑治疗胃溃疡的成本效果,为临床合理用药提供参考和建议。方法:立足医疗系统研究视角,构建决策树模型对泮托拉唑和奥美拉唑治疗胃溃疡进行成本效果分析,并对参数的不确定性进行单因素敏感性分析。结果:从平均成本效果比来看,泮托拉唑治疗胃溃疡平均每单位效果的成本为33.36元,奥美拉唑为21.18元;增量成本效果分析显示,泮托拉唑相对于奥美拉唑的增量成本效果比为131.14(ICER=131.14),增加单位治愈病例意愿支付金额小于131.14元时,最优方案为奥美拉唑,意愿支付金额大于131.14元时,最优方案为泮托拉唑。结论:临床医生可以根据胃溃疡患者意愿支付金额高低选择最优的治疗方案。
英文摘要:
      Objective: To study and evaluate the cost-effectiveness of pantoprazole versus omeprazole in the treatment of gastric ulcer by pharmacoeconomic methods, and to provide reference and suggestions for rational drug use in clinic. Methods: From the perspective of medical system, a decision tree model was established to analyze the cost-effectiveness of pantoprazole and omeprazole in the treatment of gastric ulcer, and the uncertainty of parameters was analyzed by single factor sensitivity analysis. Results: From the average cost-effectiveness ratio, the average cost per unit effect of pantoprazole in the treatment of gastric ulcer was 33.36 yuan and that of omeprazole was 21.18 yuan. Incremental cost-effectiveness analysis showed that the incremental cost-effectiveness ratio of pantoprazole to omeprazole was 131.14 (ICER=131.14). When the unit willingness to pay was less than 131.14 yuan, the optimal scheme was omeprazole. When the willingness to pay is more than 131.14 yuan, pantoprazole is the better option. Conclusion: Clinicians can choose the optimal treatment plan according to the amount of money which patient willing to pay for gastric ulcer.
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